Xenobiotic Effects on Ovarian Preantral Follicles1
نویسندگان
چکیده
منابع مشابه
Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility.
Mammalian females are born with a finite number of nonrenewing primordial follicles, the majority of which remain in a quiescent state for many years. Because of their nonrenewing nature, these "resting" oocytes are particularly vulnerable to xenobiotic insult, resulting in premature ovarian senescence and the formation of dysfunctional oocytes. In this study, we characterized the mechanisms of...
متن کاملEffects of Alginate Concentration and Ovarian Cells on In Vitro Development of Mouse Preantral Follicles: A Factorial Study
Objective In the present study, the effects of alginate (ALG) concentration and ovarian cells (OCs) on the development and function of follicles were simultaneously evaluated. MaterialsAndMethods In the first step, preantral follicles (100-130 µm in diameter) were mechanically isolated from the ovaries of 2-week-old NMRI mice, encapsulated in the absence or presence of OCs in 0.5, 0.75 and 1% A...
متن کاملEffects of lowered temperatures and media on short-term preservation of zebu (Bos indicus) preantral ovarian follicles.
The maintenance of follicle quality during the transportation of ovaries is essential for the successful cryopreservation and in vitro development of preantral follicles. The objective of this study was to evaluate the effect of cooling ovarian tissue on the conservation of zebu cow preantral follicles. Ovarian pieces were immersed in saline or coconut water (CW) solutions and maintained at 4 o...
متن کاملEffects of different freezing parameters on the morphology and viability of preantral follicles after cryopreservation of doe rabbit ovarian tissue.
OBJECTIVE To compare the effects of dimethyl sulfoxide (DMSO), 1,2-propanediol (PROH), sucrose, trehalose, concentration of cryoprotectants, equilibration method, and postseeding freezing rate on doe rabbit ovarian tissue preservation after freezing, using fractional experimental design. DESIGN Experimental prospective study. SETTING Research institute in veterinary and agronomic colleges. ...
متن کاملAn research on the isolation methods of frozen-thawed human ovarian preantral follicles.
OBJECTIVE To explore the effective isolation method for preantral follicles from human frozen-thawed ovarian tissue. METHODS The ovarian cortical tissue was frozen by direct cover vitrification (DCV). The frozen-thawed ovarian tissue was used for isolation of preantral follicles with collagenase combined with mechanical method and mechanical method alone, respectively. RESULTS 1. There was ...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2011
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.111.091173